Pronunciation: pan-TOE-pra-zole
Generic Name: Pantoprazole
Brand Name: Protonix
Protonix Delayed-Release Tablets are used for:
Treating irritation of the esophagus caused by gastroesophageal reflux disease (GERD). It may be used to treat conditions that cause your body to make too much stomach acid (eg, Zollinger-Ellison syndrome). It may also be used for other conditions as determined by your doctor.
Protonix Delayed-Release Tablets are a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.
Do NOT use Protonix Delayed-Release Tablets if:
- you are allergic to any ingredient in Protonix Delayed-Release Tablets
- you are taking dasatinib or certain HIV protease inhibitors (eg, atazanavir)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Protonix Delayed-Release Tablets:
Some medical conditions may interact with Protonix Delayed-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have low blood potassium or magnesium levels, liver problems, or stomach or bowel cancer
- if you have osteoporosis (weak bones), a family history of osteoporosis, or other risk factors of osteoporosis (eg, smoking, poor nutrition)
Some MEDICINES MAY INTERACT with Protonix Delayed-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood magnesium levels may be increased
- Clarithromycin or voriconazole because they may increase the risk of Protonix Delayed-Release Tablets's side effects
- Anticoagulants (eg, warfarin) or digoxin because the risk of their side effects may be increased by Protonix Delayed-Release Tablets
- Ampicillins, azole antifungals (eg, ketoconazole), clopidogrel, dasatinib, HIV protease inhibitors (eg, atazanavir, indinavir), iron, mycophenolate, or nilotinib because their effectiveness may be decreased by Protonix Delayed-Release Tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if Protonix Delayed-Release Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Protonix Delayed-Release Tablets:
Use Protonix Delayed-Release Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Protonix Delayed-Release Tablets by mouth with or without food.
- Swallow Protonix Delayed-Release Tablets whole. Do not break, crush, or chew before swallowing.
- You may take antacids while you are using Protonix Delayed-Release Tablets if you are directed to do so by your doctor.
- If you also take an imidazole antifungal (eg, ketoconazole), take it at least 2 hours before taking Protonix Delayed-Release Tablets.
- If you also take sucralfate, take Protonix Delayed-Release Tablets at least 30 minutes before taking sucralfate.
- Continue to take Protonix Delayed-Release Tablets even if you feel well. Do not miss any doses.
- If you miss a dose of Protonix Delayed-Release Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Protonix Delayed-Release Tablets.
Important safety information:
- Protonix Delayed-Release Tablets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Protonix Delayed-Release Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
- Protonix Delayed-Release Tablets may increase the risk of hip, wrist, and spine fractures in patients with weak bones (osteoporosis). The risk may be greater if you use Protonix Delayed-Release Tablets in high doses, for longer than a year, or if you are over 50 years old. Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor. Contact your doctor if you have any questions about this information.
- Low blood magnesium levels have been reported rarely in patients taking PPIs for at least 3 months. In most cases, this effect was seen after a year of treatment. If you will be taking Protonix Delayed-Release Tablets for a long time, or if you take certain other medicines (eg, digoxin, diuretics), your doctor may perform lab tests to check for low blood magnesium levels. Seek medical attention right away if you experience symptoms of low blood magnesium levels (eg, dizziness; fast or irregular heartbeat; involuntary muscle movements; jitteriness or tremors; muscle aches, cramps, pain, spasms, or weakness; seizures).
- Check with your doctor to see whether you should take a calcium and vitamin D supplement while you use Protonix Delayed-Release Tablets.
- Protonix Delayed-Release Tablets may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Protonix Delayed-Release Tablets.
- Protonix Delayed-Release Tablets should be used with caution in Asian patients; the risk of side effects may be increased in these patients.
- Use Protonix Delayed-Release Tablets with caution in the ELDERLY; they may be more sensitive to its effects, especially hip, wrist, and spine fractures.
- Protonix Delayed-Release Tablets should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Protonix Delayed-Release Tablets while you are pregnant. Protonix Delayed-Release Tablets are found in breast milk. Do not breast-feed while taking Protonix Delayed-Release Tablets.
Possible side effects of Protonix Delayed-Release Tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; headache; nausea; stomach pain; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, hands, eyes, throat, or tongue; unusual hoarseness); bone pain; chest pain; dark urine; fast or irregular heartbeat; fever, chills, or sore throat; red, swollen, blistered, or peeling skin; unusual bruising or bleeding; unusual tiredness; vision changes; yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Protonix side effects (in more detail)
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.
Proper storage of Protonix Delayed-Release Tablets:
Store Protonix Delayed-Release Tablets between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Protonix Delayed-Release Tablets out of the reach of children and away from pets.
General information:
- If you have any questions about Protonix Delayed-Release Tablets, please talk with your doctor, pharmacist, or other health care provider.
- Protonix Delayed-Release Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information is a summary only. It does not contain all information about Protonix Delayed-Release Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
More Protonix resources
- Protonix Side Effects (in more detail)
- Protonix Use in Pregnancy & Breastfeeding
- Drug Images
- Protonix Drug Interactions
- Protonix Support Group
- 27 Reviews for Protonix - Add your own review/rating
Compare Protonix with other medications
- Barrett's Esophagus
- Duodenal Ulcer
- Erosive Esophagitis
- GERD
- Helicobacter Pylori Infection
- Peptic Ulcer
- Stomach Ulcer
- Stress Ulcer Prophylaxis
- Zollinger-Ellison Syndrome
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